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29 January 2011 Last updated at 01:26 GMT By James Gallagher Health reporter, BBC News
Ever since medicine declared war on bacteria with the discovery of penicillin, the two have been locked in an arms race.
Antibiotics are met by resistance from germs; so researchers develop new drugs and germs become resistant again.
Now some scientists believe genetics will be the new weapon in the fight, with doctors consulting bacterial genomes when treating disease.
This week a team at the Wellcome Trust Sanger Institute published a paper in the journal Science, which they say shows the first genetic picture of the evolutionary war between medicine and bacteria.
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